Environmental Tobacco Smoke and Parkinson's Disease
Identifieur interne : 001130 ( Main/Exploration ); précédent : 001129; suivant : 001131Environmental Tobacco Smoke and Parkinson's Disease
Auteurs : Susan Searles Nielsen [États-Unis] ; Lisa G. Gallagher [États-Unis] ; Jessica I. Lundin [États-Unis] ; W. T. Jr Longstreth [États-Unis] ; Terri Smith-Weller [États-Unis] ; Gary M. Franklin [États-Unis] ; Phillip D. Swanson [États-Unis] ; Harvey Checkoway [États-Unis]Source :
- Movement disorders [ 0885-3185 ] ; 2012.
Descripteurs français
- Pascal (Inist)
- Wicri :
English descriptors
Abstract
Background: Parkinson's disease is inversely associated with cigarette smoking, but its relation with passive smoking or environmental tobacco smoke exposure is rarely examined. Methods: Within a case-control study, we assessed the association between Parkinson's disease and living or working with active smokers. Cases were newly diagnosed with idiopathic Parkinson's disease (n = 154) from western Washington State in 2002-2008. Age- and sex-matched controls (n = 173) were neurologically normal and unrelated to cases. Results: Compared with never active or passive tobacco smokers, we observed reduced Parkinson's disease risks for ever passive only smokers (OR, 0.34; 95% CI, 0.16-0.73), similar to those for ever active smokers (OR, 0.35; 95% CI, 0.17-0.73). Among persons whose only tobacco smoke exposure was passive smoking at home, risk was inversely associated with years exposed. Conclusions: These observations parallel those well established for active smoking. However, it remains unresolved whether a true protective effect of tobacco smoke, generally detrimental to health, underlies these associations.
Affiliations:
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Le document en format XML
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<series><title level="j" type="main">Movement disorders</title>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Idiopathic</term>
<term>Nervous system diseases</term>
<term>Parkinson disease</term>
<term>Pollution</term>
<term>Tobacco</term>
<term>Tobacco smoking</term>
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<keywords scheme="Pascal" xml:lang="fr"><term>Maladie de Parkinson</term>
<term>Tabagisme</term>
<term>Pathologie du système nerveux</term>
<term>Tabac</term>
<term>Pollution</term>
<term>Idiopathique</term>
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<front><div type="abstract" xml:lang="en">Background: Parkinson's disease is inversely associated with cigarette smoking, but its relation with passive smoking or environmental tobacco smoke exposure is rarely examined. Methods: Within a case-control study, we assessed the association between Parkinson's disease and living or working with active smokers. Cases were newly diagnosed with idiopathic Parkinson's disease (n = 154) from western Washington State in 2002-2008. Age- and sex-matched controls (n = 173) were neurologically normal and unrelated to cases. Results: Compared with never active or passive tobacco smokers, we observed reduced Parkinson's disease risks for ever passive only smokers (OR, 0.34; 95% CI, 0.16-0.73), similar to those for ever active smokers (OR, 0.35; 95% CI, 0.17-0.73). Among persons whose only tobacco smoke exposure was passive smoking at home, risk was inversely associated with years exposed. Conclusions: These observations parallel those well established for active smoking. However, it remains unresolved whether a true protective effect of tobacco smoke, generally detrimental to health, underlies these associations.</div>
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<name sortKey="Swanson, Phillip D" sort="Swanson, Phillip D" uniqKey="Swanson P" first="Phillip D." last="Swanson">Phillip D. Swanson</name>
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